Most of us are well aware of Hypertension, as it is one of the major non-communicable disease burdening today’s world and is usually defined as blood pressure of more than 140/90mmHg, the values signifying the systolic blood pressure and the diastolic blood pressure respectively. This entity is better termed as Systemic Hypertension.
But at some point of time, you may have come across the term Pulmonary Hypertension. Lets get a brief insight of this disease.
Pulmonary Hypertension is a rare disease spectrum that occurs due to increased pressures particularly in the lung vasculature. It is defined as mean Pulmonary Artery Pressure of more than 25mmHg or systolic Pulmonary Artery pressure more than 36mmHg.
Causes, Associations and Risk Factors
Clinical Presentation or Symptoms
The disease may initially present with symptoms like fatigue, shortness of breath, chest pain, or syncope.
But as the disease progresses, it leads to right sided heart failure, and the symptoms like edema of feet and ankles, distension of abdomen, swelling of neck veins may become more evident.
As the disease presents with non-specific symptoms, an absolute clinical diagnosis is not possible.
On diagnosis, the disease warrants treatment as without treatment, the prognosis may not be favourable.
In most of the cases, the treatment of the disease is done by treating the underlying cause of the disease. For example: Oxygen therapy, Diuretics, Anticoagulants, etc.
There is no definitive cure for Pulmonary Hypertension. However, few medications have been approved for the treatment of the disease, which mainly aim at dilating the vessels in the pulmonary vasculature. As per studies, these medications have proven to reduce morbidity, and in some cases, even the mortality.
There are three main group of medications being used: